Immiscible two-phase flow through porous media is composed of a series of pore invasions; however, the consequences of pore-scale processes on macroscopic fluid front behavior remain to be clarified. In this work, we perform an analytical and experimental investigation of front behavior and pore invasions dynamics during drainage for various viscosity ratios and capillary numbers. We use a microfluidic setup that includes a fully controlled pore-doublet geometry to isolate and explore pore-invasion mechanisms. We apply a model based on volume-averaged Navier–Stokes equation to capture interface dynamics. Different invasion mechanisms are characterized and correlated with front behavior for various flow conditions. For the viscous flow regime, a succession of continuous pore invasions is observed, leaving a thick layer of wetting phase behind at pore curvatures. Abrupt interfacial jumps, followed by an apparent stagnant condition, are observed for the capillary flow regime. We identified a new regime, called crossover flow regime, for which pore invasion shows a mixed behavior between capillary and viscous dominated regimes. The global front behavior is predicted based on the numerical simulation and experimental results for all flow regimes.