The S wave velocity distribution in the Earth's crust and the first two hundred kilometers of the upper mantle is inferred from data of a seismological linear network including 18 broadband stations installed in the framework of the international teleseismic experiment carried out in 2003 in the south of Siberia and in Mongolia. Models were constructed by using P-to-S received function inversion beneath each station. Vertical cross sections of S wave velocities from the surface to depths of 65 and 270 km covering the entire 1000-km profile are constructed by the linear spline interpolation of individual velocity models. The vertical sections are also represented as anomalies relative to the standard velocity model. The most intense low velocity anomalies (from −3 to −6%) in the crust and upper mantle are identified beneath the Sayan, Khamar-Daban, and Khangai highlands and the Djida fold zone and agree both with other geophysical data and with the distribution of Late Cenozoic volcanic fields. The results of this work suggest that the activation of Mongolian-Siberian highlands is largely connected with uplift of the asthenosphere to the base of the crust.