The French alpine foreland area has been struck by several earthquakes with magnitudes above 5 on Richter scale in recent history. In this paper we document the regional impact of historical and Holocene earthquakes based on the identification of mass wasting deposits in glacial lakes at different settings. Lake Le Bourget and Lake Paladru are situated at low elevations (respectively 231 m–492 m) and Lake Blanc Huez is located at 2500 m altitude. Through the integration of high-resolution acoustic profiles and accurately dated sediment samples from cores, recent coeval mass wasting deposits in each lake were correlated with nearby historical earthquakes, whereas coeval mass wasting deposits around 5200 cal BP and 9550 cal BP in these three lakes were correlated to regional earthquakes events.