Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure - INSU - Institut national des sciences de l'Univers Access content directly
Journal Articles Coatings Year : 2019

Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure

Abstract

In this study, ZnHAp layers deposited on a Si substrate were obtained by a sol-gel spin-coating procedure. The ZnHAp solutions used to obtain the ZnHAp coatings were investigated by dynamic light scattering (DLS) analysis, ζ-potential, ultrasound measurements, and flame atomic absorption spectrometry (AAS). The average measured hydrodynamic diameter from the DLS analysis, ζ-potential, and ultrasound measurements were analyzed so as to characterize and estimate the stability of the ZnHAp nanoparticles. The AAS results confirmed the presence of zinc in the gels used in the preparation of the ZnHAp layers. The layers were investigated by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The XRD results revealed the diffraction peaks of the hexagonal hydroxyapatite in all of the investigated samples. The morphology of the ZnHAp coatings annealed at 500 • C (ZnHAp-500) and 700 • C (ZnHAp-700), which evidenced that no fissures or cracks formed on the surface of the coatings. The biocompatibility assays indicated that the ZnHAp coatings did not present any toxicity towards the HeLa cells. Furthermore, the study regarding the cytotoxicity of the ZnHAp layers against microorganisms emphasized that ZnHAp coatings exhibited an inhibitory effect towards S. aureus bacterial cells and also towards C. albicans fungal cells.
Fichier principal
Vignette du fichier
coatings-09-00156.pdf (5.77 Mo) Télécharger le fichier
Origin : Publisher files allowed on an open archive
Loading...

Dates and versions

insu-02058905 , version 1 (06-03-2019)

Identifiers

Cite

Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Nicolas Buton, Mikael Motelica-Heino. Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure. Coatings, 2019, 9 (3), pp.156. ⟨10.3390/coatings9030156⟩. ⟨insu-02058905⟩
79 View
105 Download

Altmetric

Share

Gmail Facebook X LinkedIn More