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Structure: Internal structure identifier : 203895

An enzyme-responsive system programmed for the double release of bioactive molecules through an intracellular chemical amplification process

M. Grinda , T. Legigan , J. Clarhaut , E. Peraudeau , I. Tranoy-Opalinski , et al.
Organic & Biomolecular Chemistry, 2013, 11 (41), pp.7129-7133. ⟨10.1039/c3ob41536h⟩
Journal articles hal-00966980v1

Impact of operation conditions, foulant adsorption, and chemical cleaning on the nanomechanical properties of ultrafiltration hollow fiber membranes

Audrey Allavena , Sylvie Liu , Thomas Ribette , Ninette Abou Mrad , Thierry Chiavassa , et al.
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, 549, pp.34-42. ⟨10.1016/j.colsurfa.2018.04.003⟩
Journal articles hal-02121394v1
Image document

A galactosidase-responsive doxorubicin-folate conjugate for selective targeting of acute myelogenous leukemia blasts

Jonathan Clarhaut , Sylvain Fraineau , Joëlle Guilhot , Elodie Péraudeau , Isabelle Tranoy-Opalinski , et al.
Leukemia Research, 2013, 37 (8), pp.948 - 955. ⟨10.1016/j.leukres.2013.04.026⟩
Journal articles inserm-02444614v1

Etude de l’effet du premier vecteur glucuronylé de la cyclopamine sur les cellules initiatrices de glioblastomes

Anais Balbous , Thibaut Legigan , Brigitte Renoux , Ulrich Cortes , Pierre Rivet , et al.
6ème journée du Cancéropole Grand-Ouest Tours-Poitiers, Angers, Jun 2012, Angers, France
Conference poster hal-02538745v1

The First Generation of β-Galactosidase-Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy

Thibaut Legigan , Jonathan Clarhaut , Isabelle Tranoy-Opalinski , Arnaud Monvoisin , Brigitte Renoux , et al.
Angewandte Chemie International Edition, 2012, 51, pp.1 - 6. ⟨10.1002/anie.201204935⟩
Journal articles istex hal-00736090v1

beta-Glucuronidase-responsive prodrugs for selective cancer chemotherapy: An update

Isabelle Tranoy-Opalinski , Thibaut Legigan , Romain Barat , Jonathan Clarhaut , Mikael Thomas , et al.
European Journal of Medicinal Chemistry, 2014, 74, pp.302-313. ⟨10.1016/j.ejmech2013.12.045⟩
Journal articles hal-01196935v1

Study of a novel agent for TCA precipitated proteins washing - comprehensive insights into the role of ethanol/HCl on molten globule state by multi-spectroscopic analyses

Claude Geffroy-Rodier , Balkis Eddhif , Justin Lange , Nadia Guignard , Yann Batonneau , et al.
Journal of Proteomics, 2018, 173, pp.77 - 88. ⟨10.1016/j.jprot.2017.11.016⟩
Journal articles insu-01823781v1

Synthesis and biological evaluations of a monomethylauristatin E glucuronide prodrug for selective cancer chemotherapy

Thibaut Legigan , Jonathan Clarhaut , Brigitte Renoux , Isabelle Tranoy-Opalinski , Arnaud Monvoisin , et al.
European Journal of Medicinal Chemistry, 2013, 67, pp.75-80. ⟨10.1016/j.ejmech.2013.06.037⟩
Journal articles hal-04033523v1

Etude de l’effet du premier vecteur glucuronylé de la cyclopamine sur les cellules initiatrices de glioblastomes

Anais Balbous , Thibaut Legigan , Brigitte Renoux , Ulrich Cortes , Pierre Rivet , et al.
6ème colloque du Cancéropole PACA- Glioblastomes, Feb 2012, Marseille, France
Conference poster hal-02538740v1
Image document

Enhancing tumor response to targeted chemotherapy through up-regulation of folate receptor α expression induced by dexamethasone and valproic acid

E. Peraudeau , L. Cronier , A. Monvoisin , P. Poinot , C. Mergault , et al.
Journal of Controlled Release, 2018, 269, pp.36-44. ⟨10.1016/j.jconrel.2017.11.011⟩
Journal articles hal-02122599v1