This paper discusses the nature and origin of subsurface sediment mobilization processes in deep marine clay-rich environments. In the studied area of the southern Barbados accretionary prism, new geophysical acquisitions have emphasized the spectacular widespread development of mud volcanoes that are well-developed along ramp anticlines and along sigmoidal rises with trends that are oblique to the axes of the main folds of the accretionary wedge. On some active mud volcanoes, heat-flow measurements show high positive anomalies related to high fluxes of mud transfer. The mobilized solid fraction expelled by the mud volcanoes does not originate from a unique source bed but from various formations pierced by the mud conduits and is driven by the water phase. The area studied also exhibits trends of structures corresponding to sub-circular massive local uplifts of deformed but well-preserved stratified sediments (turbidites and hemipelagics). No piercing shale diapirs have been encountered in this area. Some of these local uplift structures are complicated by the development of collapses, calderas, and superimposed mud volcanoes. Mud volcanism corresponds fundamentally to fluid displacement (water and gas), whereas massive sedimentary uplift corresponds to large vertical displacements of stratified solid levels but for which the deep cause could be partly the intrusion of mud plugs. Both are dynamic phenomena controlled by the development of overpressure at depth, contributing to sedimentary mobilizations.