We present the first stable isotope paleoaltimetry estimates for the hinterland of the eroded Variscan Belt of Western Europe based on the hydrogen isotope ratios of muscovite from syntectonic leucogranites that have been emplaced at ~315 Ma. We focus on the Limousin region (Western Massif Central, France) where peraluminous granites are spatially associated with strike-slip and detachment shear zones that developed as a consequence of Late Carboniferous syn- to post-orogenic extension and merge to the northwest with the South Armorican Shear Zone. Here we show that the NE corner of the Millevaches massif located at the junction between brittle and ductile fault systems represented a pathway for Earth surface-derived fluids that penetrated the crust and reached the ductile segment of the low-angle Felletin detachment zone. Using microstructural, thermometry, hydrogen isotope geochemistry and 40Ar/39Ar geochronological data, we show that these Variscan meteoric fluids interacted with hydrous silicates during high temperature deformation between at least ~318 and 310 Ma. For paleoaltimetry purposes, we reference our hydrogen isotope record (δD) of ancient meteoric fluids from mylonitic rocks to ~295 Myr-old records retrieved from freshwater shark remains preserved in the Bourbon l’Archambault basin that developed in the external zones of the orogen. A ~76‰ difference in δDmeteoric water values between the Millevaches massif (δDmeteoric water value = -96 ± 8‰) and the Bourbon l’Archambault foreland basin (δDwater value = -20 ± 6‰) is consistent with minimum paleoaltimetry estimates of 3400 ± 700 m based on a modern lapse rate of ~-22‰/km for δDwater values. The rather large difference in δD values between the foreland basin and the continental interior suggests that the hinterland of the Variscan belt of western Europe was high enough to act as a barrier to moisture transport from the south-south-east and induce an orographic rain shadow to the north.