In Western Europe, the deformations related to the opening of the Bay of Biscay and the formation of the Pyrenean belt are well described in the southern part of the Aquitaine basin, but little is known about the impact of these geodynamic events towards the Northern Aquitaine Platform. In this paper, we combine field observation with Unmanned Aerial Vehicle (UAV) imagery and calcite U-Pb geochronology to determine precisely the tectonic evolution in the Vendée Coastal domain. We evidence two main tectonic events: (1) At the transition between the Late Jurassic to Early Cretaceous, WNW-ESE striking normal faults formed horsts and grabens at the onset of the opening of the Bay of Biscay. The reactivation of Variscan faults during this tectonic event is consistent with oblique extension. This event triggered ascending fluid flows that mix with basin fluids responsible for baritepyrite-quartz mineralizations near the unconformity. (2) During the Late Cretaceous, fractures, wide-open folds, veins, and joints are consistent with the N-S shortening direction during the earliest stages of the Pyrenenan compression. In both cases, the Northern Aquitaine Platform records the early stages of the main regional tectonic events in a far-field position. In the northern Aquitaine Basin, as in many other places in Europe, the tectonic study of sedimentary platforms located far from the plate boundaries provides new constraints on the early diffuse deformation process that predate the main tectonic phases.