The Afar depression at the northern end of the East African Rift system is presently experiencing the final stage of continental break-up and progressive onset of steady magmatic spreading. The Magmatic Rift Segments in Afar broadly analogous to those observed within the mid oceanic ridges, offer the opportunity to study both mantle and crustal processes. Investigating the crustal architecture of those magmatic segments represents a key aspect to decipher fundamental parameters that control focussing of magmatic and tectonic activity during the generation of magmatic crust. Here, we present the typical organization of a 32 km long subsegment of the Manda Hararo magmatic rift system, with fissural activities symmetrical to an apparent mid segment magmatic reservoir and establish geochronology of the last eruptive history. We combine field investigations, precise mapping of volcanological and tectonic features, cosmogenic 36Cl exposure dating and geochemical analysis of lavas to constrain the temporal frame and the dynamics of magmatic processes. Our results show that the recent historical volcanic events (~ 500 to 2000 years) are sourced from calderas and fissures representing an alternating sequence of effusive and explosive (block fields) activities related to a coherent rifting episode along a single self-consistent magmatic sub-segment. Those recent fissural flows resurfaced a large portion of the segment and emplaced on older thick pahoehoe flows with a rather long lag-time of about 75 kyr separating the two episodes. Strongly contrasted geochemical signatures are also observed between those two volcanic episodes, with more differentiated and trace elements enriched basalts for the recent one, compared to the older one which are characterized by a unusual depleted signature. These new results for the Central Afar Manda Hararo rift have important implications for: (i) the local hazards along the segments, and (ii) the volcano-tectonic organization of the segment with coexistence of contrasted melt reservoirs on the underlying transcrustal plumbing system.