Negative pressure in liquids is both an experimental fact and a usually-neglected state of condensed matter. Using synthetic fluid inclusions, namely closed vacuoles fabricated inside one solid host by hydrothermal processes, a Raman study was performed to examine how a superheated solvent (under negative pressure) interacts with its dissolved solutes. As a result, this contribution not only illustrates this well-known tensile state, but also displays evidence that a stretched solvent is able to pull on its dissolved solutes and put them also under a stretched state. The dielectric continuum hypothesis may lead to expect a stretching effect in solutes similar to the solvent’s, but our measurements evidence a damping mechanical effect (growing with tension), most probably related to solvation shells. One practical consequence is that the (experimentally known) super-solvent properties of superheated solutions are certainly related to the change of the chemical potential of solutes which results from the damping effect. This change can determine as well a change in the thermodynamic driving force of the superheated solution towards bubble nucleation. A more complex than usual picture of the aqueous solution physical chemistry emerges from this study.